ABSTRACT
Glabratephrin, flavonoid of 7-oxygenated-8 prenyl-flavones has been isolated from the seeds of Tephrosia nubica for the first time. It showed significant antimicrobial and analgesic activities with no ulcerations
Subject(s)
Animals, Laboratory , Plants/chemistry , Plants, Medicinal/chemistry , Seeds/chemistry , Rats , Carrageenan , Plant Extracts/chemistryABSTRACT
The crude protein of the Nelumbo nucifera seeds were found to be 14.81%. The essential amino acids using the amino acid analyzer were threonine 2.43%, methionine 0.82%, leucine 3.33%, isoleucine 1.11% and phenylalanine 12.64%. The semi-essential amino acids were arginine 7.45% and histidine 10.79%. Other amino acids were found in adequate amount as glutamic 26.56%, proline 10.76%, aspartic 6.17%, tyrosine 4.65%, serine 4.27%, glycine 2.43%, alanine 2.77% and cysteine 3.71%. Moreover, the crude protein caused a significant decrease [44.80%] in the blood glucose level of diabetic albino rats after two weeks of treatment
Subject(s)
Animals, Laboratory , Plants/chemistry , Amino Acids/analysis , Plants, Medicinal/chemistry , Seeds/chemistry , Hypoglycemic Agents/pharmacology , Drug EvaluationABSTRACT
Six flavonol glycosides; namely, quercetin 3-O-galactoside, patuletin 3-O-rutinoside, isorhamnetin, patuletin 3-O-glucoside, kaempferol-7-O-rutinoside together with the rare flavonol patuletin were isolated from the methanolic extract 70% of the aerial parts of Urtica urens L. They were identified using spectroscopic techniques. The aglycon patuletin which represents the major compound was tested for its antimicrobial properties as well as anti-inflammatory, analgesic and ulcerogenic effects